The HMGB1 C-Terminal Tail Regulates DNA Bending
نویسندگان
چکیده
منابع مشابه
Role of the Acidic Tail of High Mobility Group Protein B1 (HMGB1) in Protein Stability and DNA Bending
High mobility group box (HMGB) proteins are abundant nonhistone proteins found in all eukaryotic nuclei and are capable of binding/bending DNA. The human HMGB1 is composed of two binding motifs, known as Boxes A and B, are L-shaped alpha-helix structures, followed by a random-coil acidic tail that consists of 30 Asp and Glu residues. This work aimed at evaluating the role of the acidic tail of ...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2016
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2016.08.018